Basic Information
VIS ID
TVIS30012766
Fusion event
HIV-TLK1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
171884425/171027915 (Hg38)
End
171884425/171027915 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
TLK1
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-28-5p ; hsa-mir-374b-3p ; hsa-mir-5696 ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-1909-5p ; hsa-mir-4729 ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-646 ; hsa-mir-5586-3p ; hsa-mir-503-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-1305 ; hsa-mir-421 ; hsa-mir-505-3p ; hsa-mir-7159-5p ; hsa-mir-4660 ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-4801 ; hsa-mir-4731-3p
Nearest miRNA
hsa-mir-128-1/Upstream/2444897; hsa-mir-10b/Downstream/4139718;
Nearest TSS
ENST00000437798/Upstream/74097; ENST00000495925/Downstream/27214;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/53717, chr2-CpG: 126/Downstream/132113
Upstream sequence
ATTTTTAAGTTGACACAAGATAAAGGAATGTTGTTTTAATATACTCAACATAAAAATGTAATTTTggccgggtgcgacagctcatgcctgtaatcccagc
Downstream sequence
accttgggaggccaaggtgggtggatcacacgaagccaggagtttgagaccagcctggtgaacatggcgaaaccctcactctactaaaaatacaaaaatt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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