Basic Information
VIS ID
TVIS30012793
Fusion event
HIV-CASP10 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
202074738/201210015 (Hg38)
End
202074738/201210015 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
CASP10
miRNAs that regulate target gene
hsa-mir-624-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-4775 ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-4735-5p ; hsa-mir-6765-3p ; hsa-mir-1228-3p ; hsa-mir-1272 ; hsa-mir-329-5p ; hsa-mir-590-3p ; hsa-mir-580-5p ; hsa-mir-592 ; hsa-mir-8057 ; hsa-mir-197-3p ; hsa-mir-597-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-140-3p ; hsa-mir-34a-5p ; hsa-mir-4656 ; hsa-mir-4697-3p ; hsa-mir-8077
Nearest miRNA
hsa-mir-10b/Upstream/12076904; hsa-mir-1244-1/Downstream/5573219;
Nearest TSS
ENST00000437798/Upstream/22269; ENST00000490682/Downstream/23428;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/91029, chr2-CpG: 110/Downstream/241115
Upstream sequence
atagacggggaagggcatccccagctggtaagtgcacattgtgaagtataggtgttatgggaacatgcagaatgagtaccttgcccagatttgaaggatc
Downstream sequence
agaggaggcttctagaaatgacaaatagatgttaggtaaagaatcaggtgaaagatgtgctgggcagagggaatagcatgaacaaaagcatgggggcCTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate