Basic Information
VIS ID
TVIS30012808
Fusion event
HIV-TRIP12 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
230730373/229865657 (Hg38)
End
230730373/229865657 (Hg38)
Orient
-
Location type
Intronic
Target gene
TRIP12
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-193b-3p ; hsa-mir-106b-5p ; hsa-mir-149-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-10b/Upstream/2393470; hsa-mir-1244-1/Downstream/1497051;
Nearest TSS
ENST00000437798/Upstream/6375; ENST00000465090/Downstream/55701;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/150392, chr2-CpG: 150/Downstream/55539
Upstream sequence
ATGCATATATTACCAAATATAAATGGATTGTGGGTTTAATTACAACTCTAAATTTGTTTGTGTATATGTGTATACAGACACATTTTTATGCTTTTCTACT
Downstream sequence
TTAAATACACAATTATAACATTATAGTTTTGTCTTCTAAAAATTAGATATTTTATTTCAAATGCTGGAAAATCCATGTTTTAAAAGAGCCATTGATTTTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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