Basic Information
VIS ID
TVIS30012931
Fusion event
HIV-MORC3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.12
Reference genome
GRCh37/hg19
Start
37728913/36356615 (Hg38)
End
37728913/36356615 (Hg38)
Orient
-
Location type
Intronic
Target gene
MORC3
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-101-3p ; hsa-mir-32-5p ; hsa-mir-21-5p ; hsa-mir-197-3p ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-218-2-3p ; hsa-mir-30e-3p ; hsa-mir-545-5p ; hsa-mir-584-5p ; hsa-mir-622 ; hsa-mir-758-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-144-3p ; hsa-mir-5700 ; hsa-mir-153-3p
Nearest miRNA
hsa-let-7c/Upstream/635807; hsa-mir-3197/Downstream/3090395;
Nearest TSS
ENST00000624081/Upstream/8743; ENST00000484028/Downstream/5221;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/35854, chr21-CpG: 63/Downstream/28583
Upstream sequence
TTTGGAGTTTTTTCTCTTCACAGTGTCTATGTACTCATTACTAGATTATTTATGATTTATGTTTGAAAAGAATTTTTTCTTGATTTTATGATTTACTTTT
Downstream sequence
TAAGACTTACAATAACAGCACTAGGAGAAAAGCTGAATGATTACTGGAATGAAATGAAAGTGAAGAAAAATACAGAATATCCTCTAAATTTGCCAGTTGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate