Basic Information
VIS ID
TVIS30012943
Fusion event
HIV-IL17RA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
17573089/17092199 (Hg38)
End
17573089/17092199 (Hg38)
Orient
-
Location type
Intronic
Target gene
IL17RA
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-92a-3p ; hsa-mir-3978 ; hsa-mir-6807-5p ; hsa-mir-7160-5p ; hsa-mir-7854-3p ; hsa-mir-6134 ; hsa-mir-6823-3p ; hsa-mir-2114-3p ; hsa-mir-7162-3p ; hsa-mir-135b-5p ; hsa-mir-135a-5p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-498 ; hsa-mir-5001-3p ; hsa-mir-4279 ; hsa-mir-4772-3p ; hsa-mir-3653-5p ; hsa-mir-10b-3p ; hsa-mir-5571-5p
Nearest miRNA
hsa-let-7a-3/Downstream/671981;
Nearest TSS
ENST00000624155/Upstream/7142; ENST00000428078/Downstream/29054;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/6099, chr22-CpG: 77/Downstream/16351
Upstream sequence
tgaaggccccctgaagttgcaatggccagtggtttaatcagtcatgctcacatgaagcctccataaaaacggggttcagagagcttccaggtagtggaac
Downstream sequence
atgtggaggttcctggagggtggcacacctgaggagggcatggaagctttgtactccttctcctatacctcaccttttcttctgtattatttgtgatatc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate