Basic Information
VIS ID
TVIS30012985
Fusion event
HIV-TOMM22 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
39080362/38684357 (Hg38)
End
39080362/38684357 (Hg38)
Orient
-
Location type
UTR3
Fragile sites / regions
FRA22A
Target gene
TOMM22
miRNAs that regulate target gene
hsa-mir-24-3p ; hsa-mir-296-3p ; hsa-mir-99a-5p ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-2355-5p ; hsa-mir-6731-3p ; hsa-mir-6887-3p ; hsa-mir-4778-5p ; hsa-mir-3938
Nearest miRNA
hsa-mir-1286/Upstream/695504; hsa-let-7a-3/Downstream/2129526;
Nearest TSS
ENST00000624155/Upstream/2185; ENST00000470836/Downstream/4966;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/1962, chr22-CpG: 159/Downstream/16011
Upstream sequence
GAAACAGACAAAATGCATTACACCTGTAGTGTAAAGTGGCCACTATGAATCCCTATGTATGAGAGGAGGGAGGCAGGCTGCAGCTTCAGCCACAGAATGG
Downstream sequence
GGACTATGGAAGACAGCAGGAGCTCATTTCCTCTGCACATTTTGGCTGTTAGACCTGTGTGTGTGTTTAAAAAAAGAGAAGTCAGTGCTCACTTTTTGTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate