Basic Information
VIS ID
TVIS30013112
Fusion event
HIV-FHIT integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
60020082/60034356 (Hg38)
End
60020082/60034356 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3B
Target gene
FHIT
miRNAs that regulate target gene
hsa-mir-143-3p ; hsa-mir-217 ; hsa-mir-331-3p ; hsa-mir-625-5p
Nearest miRNA
hsa-let-7g/Upstream/4181762; hsa-mir-12124/Downstream/583449;
Nearest TSS
ENST00000440867/Upstream/20206; ENST00000475527/Downstream/46484;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/984138, chr3-CpG: 48/Downstream/1216576
Nearest cancer related gene
FHIT(TSG, No orient, 0)
Upstream sequence
aatGAACATGTCATTCAGATGAATTGTGCAGGTTGGCCAGCTGGCTGGCTCACACACACATACAGGGCAATTCTTGCTTTTACTTACTGAAAGGTCTTTA
Downstream sequence
AACACCACCTTTCCCTTTCAAGTAGGAGACTAAAACGTCACAGGAATTTAATTATCTGTAGGCAAGAAGATGATATGATCAAGAAAATGCTACATTTAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate