Basic Information
VIS ID
TVIS30013185
Fusion event
HIV-ZNF141 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
336327/342538 (Hg38)
End
336327/342538 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF141
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-1273e ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-4722-5p ; hsa-mir-6134 ; hsa-mir-219b-3p ; hsa-mir-4740-3p ; hsa-mir-4768-3p ; hsa-mir-302f ; hsa-mir-665 ; hsa-mir-7160-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6078 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-25-5p ; hsa-mir-3160-3p ; hsa-mir-4324 ; hsa-mir-4487 ; hsa-mir-455-3p ; hsa-mir-558 ; hsa-mir-6087 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-658 ; hsa-mir-6761-5p
Nearest miRNA
hsa-mir-12113/Downstream/7619;
Nearest TSS
ENST00000502981/Upstream/4703; ENST00000579770/Downstream/35501;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/4259, chr4-CpG: 38/Downstream/43572
Upstream sequence
GTGTGCTGTGTCTGCTTTCTCTAACTGAGTGGTACTATAATGGGTCTAGAGGGaggagcgtcagcattaacaggagacttgctgtaaaaagctaattcat
Downstream sequence
ggacccttttcaaacctgcagaatTTTGTTACTTACAGTGAGGCCTACAATATCAAATAATGTATATGTACAATGAAGCTTGAGAGGCAGTGCTTAGCTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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