Basic Information
VIS ID
TVIS30013217
Fusion event
HIV-UBE2K integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
GRCh37/hg19
Start
39734197/39732577 (Hg38)
End
39734197/39732577 (Hg38)
Orient
+
Location type
Intronic
Target gene
UBE2K
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-26b-5p ; hsa-mir-186-5p ; hsa-mir-190a-3p ; hsa-mir-24-3p ; hsa-mir-155-3p ; hsa-mir-337-5p ; hsa-mir-4485-3p ; hsa-mir-4667-3p ; hsa-mir-4495 ; hsa-mir-4670-3p ; hsa-mir-379-3p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-3679-3p ; hsa-mir-600 ; hsa-mir-6826-3p ; hsa-mir-1273e ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-3924 ; hsa-mir-6759-3p ; hsa-mir-3662 ; hsa-mir-4446-5p ; hsa-mir-374a-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-1250-3p ; hsa-mir-660-5p ; hsa-mir-4700-3p ; hsa-mir-1273d
Nearest miRNA
hsa-mir-12113/Upstream/320603; hsa-mir-1243/Downstream/769463;
Nearest TSS
ENST00000502981/Upstream/34249; ENST00000515550/Downstream/115984;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/34078, chr4-CpG: 23/Downstream/37482
Upstream sequence
ATATCATTTCACTGAGAGATGGCCTTGGAAATACATTAGAACCGCTTTGAGTTCTTCACTGTTGGTTGTTGACAATAATGTTTTTTTTATCTCATTCAAA
Downstream sequence
TTAGCTTCAACGTTATGTGCTATTTTGCATGCTTCATGTATATCTTAATAAAATAGTTGATTTGAAAATTGCTAACTTCTATAGCTTCTTCCCTCttttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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