Basic Information
VIS ID
TVIS30013272
Fusion event
HIV-TMEM131L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
154459327/153538175 (Hg38)
End
154459327/153538175 (Hg38)
Orient
-
Location type
Intronic
Target gene
TMEM131L
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-744-5p ; hsa-mir-335-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-5007-3p ; hsa-mir-5092 ; hsa-mir-3163 ; hsa-mir-513b-3p ; hsa-mir-548n ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-606 ; hsa-mir-4684-5p ; hsa-mir-3675-3p ; hsa-mir-4724-5p ; hsa-mir-216b-5p ; hsa-mir-3150b-5p ; hsa-mir-3150a-5p
Nearest miRNA
hsa-mir-12113/Upstream/1001659; hsa-mir-1305/Downstream/5590627;
Nearest TSS
ENST00000502981/Upstream/71826; ENST00000462540/Downstream/16006;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/70712, chr4-CpG: 95/Downstream/145759
Upstream sequence
TCGGTATTTGAGGATGTTTTAAGCAATCTTCAAAGAGTAGGATAATTCTTACCCCTTGCCTTCCCTGAAATGTAAATGGCAGTGGTTCTTATTGACTATG
Downstream sequence
CTCCTTCCAGGACTTTGTTCCTTCCAGGTGGGGATGTCACCTGTGTGCTCCTTCTAGCACCTCTTTTCTTTCTGGTGTGGCCACATCAGTCTGGAATACC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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