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Viral Integration Site DataBase
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TVIS30013341
Basic Information
VIS ID
TVIS30013341
Fusion event
HIV-PPP2CA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
133539726/134204035 (Hg38)
End
133539726/134204035 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5C
Target gene
PPP2CA
miRNAs that regulate target gene
hsa-mir-340-3p
;
hsa-mir-197-3p
;
hsa-mir-153-5p
;
hsa-mir-4777-5p
;
hsa-mir-526a
;
hsa-mir-523-5p
;
hsa-mir-522-5p
;
hsa-mir-520c-5p
;
hsa-mir-519c-5p
;
hsa-mir-519b-5p
;
hsa-mir-519a-5p
;
hsa-mir-518f-5p
;
hsa-mir-518e-5p
;
hsa-mir-518d-5p
;
hsa-mir-4766-3p
;
hsa-mir-3152-3p
;
hsa-mir-4305
;
hsa-mir-889-3p
;
hsa-mir-107
;
hsa-mir-103a-3p
;
hsa-mir-545-3p
;
hsa-mir-96-3p
;
hsa-mir-5583-3p
;
hsa-mir-4517
;
hsa-mir-3646
;
hsa-mir-548c-3p
;
hsa-mir-8081
;
hsa-mir-6869-5p
;
hsa-mir-185-3p
;
hsa-mir-4283
;
hsa-mir-4656
;
hsa-mir-4489
;
hsa-mir-5186
;
hsa-mir-3675-5p
;
hsa-mir-9500
;
hsa-mir-6822-5p
;
hsa-mir-6750-5p
;
hsa-mir-5584-5p
;
hsa-mir-548g-3p
;
hsa-mir-548av-3p
;
hsa-mir-630
;
hsa-mir-4670-3p
;
hsa-mir-7705
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-4694-3p
;
hsa-mir-6079
;
hsa-mir-584-5p
;
hsa-mir-92a-1-5p
;
hsa-mir-671-5p
;
hsa-mir-6828-5p
;
hsa-mir-758-5p
;
hsa-mir-218-2-3p
;
hsa-mir-33a-3p
;
hsa-mir-670-5p
;
hsa-mir-4732-3p
;
hsa-mir-345-3p
;
hsa-mir-3133
;
hsa-mir-553
;
hsa-mir-188-5p
;
hsa-mir-4319
;
hsa-mir-6866-3p
;
hsa-mir-125b-5p
;
hsa-mir-125a-5p
;
hsa-mir-186-3p
;
hsa-mir-216a-5p
;
hsa-mir-513c-5p
;
hsa-mir-514b-5p
;
hsa-mir-548as-3p
;
hsa-mir-548u
;
hsa-mir-7161-5p
;
hsa-mir-8087
Nearest miRNA
hsa-mir-10397/Upstream/776329; hsa-mir-103a-1/Downstream/21722;
Nearest TSS
ENST00000502646/Upstream/1550;
ENST00000602919/Downstream/20358;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/26606
,
chr5-CpG: 140/Downstream/21414
Nearest cancer related gene
PPP2CA
(TSG, No orient, 0)
Upstream sequence
TCTTAAAGGTAGCACATTCATTCCTCTGAGCACTGGGATTCATCCTGGGTTTTTAGCACAGGTTAGCTCTTTTCATAGTATTTGGAGTCACCGCAGAAAC
Downstream sequence
CTTCCaccatctagtccaactccttcattttacagatgcagaaaataaCGATCTCCAAAAATATTTCGTAGGACTTTACACAATTCAGATATTAATCAAG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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