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TVIS30013345
Basic Information
VIS ID
TVIS30013345
Fusion event
HIV-SMAD5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
135491686/136155997 (Hg38)
End
135491686/136155997 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5C
Target gene
SMAD5
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-124-3p
;
hsa-mir-130a-3p
;
hsa-mir-186-5p
;
hsa-mir-16-5p
;
hsa-mir-135a-5p
;
hsa-mir-145-5p
;
hsa-mir-135b-5p
;
hsa-mir-17-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-559
;
hsa-mir-548b-5p
;
hsa-mir-548a-5p
;
hsa-mir-548c-5p
;
hsa-mir-548d-5p
;
hsa-mir-548j-5p
;
hsa-mir-548h-5p
;
hsa-mir-548i
;
hsa-mir-548w
;
hsa-mir-548y
;
hsa-mir-548o-5p
;
hsa-mir-548ab
;
hsa-mir-548ad-5p
;
hsa-mir-548ae-5p
;
hsa-mir-548ak
;
hsa-mir-548am-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548as-5p
;
hsa-mir-548au-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548bb-5p
;
hsa-mir-3133
;
hsa-mir-377-5p
;
hsa-mir-329-5p
;
hsa-mir-655-5p
;
hsa-mir-1304-5p
;
hsa-mir-2052
;
hsa-mir-6086
;
hsa-mir-7856-5p
;
hsa-mir-4742-3p
;
hsa-mir-299-3p
;
hsa-mir-3658
;
hsa-mir-8055
;
hsa-mir-3653-3p
;
hsa-mir-4477a
;
hsa-mir-675-3p
;
hsa-mir-4766-3p
;
hsa-mir-657
;
hsa-mir-548p
;
hsa-mir-548l
;
hsa-mir-8054
;
hsa-mir-548k
;
hsa-mir-548av-5p
;
hsa-mir-4322
;
hsa-mir-4296
;
hsa-mir-4265
;
hsa-mir-4417
;
hsa-mir-6721-5p
;
hsa-mir-4736
;
hsa-mir-3692-3p
;
hsa-mir-4511
;
hsa-mir-4279
;
hsa-mir-6881-3p
;
hsa-mir-302a-5p
;
hsa-mir-877-3p
;
hsa-mir-222-3p
;
hsa-mir-548a-3p
;
hsa-mir-23a-3p
;
hsa-mir-27a-3p
;
hsa-mir-34a-3p
;
hsa-mir-3659
;
hsa-mir-4252
;
hsa-mir-4668-3p
;
hsa-mir-5690
;
hsa-mir-6889-3p
Nearest miRNA
hsa-mir-10397/Upstream/352922; hsa-mir-103a-1/Downstream/1491575;
Nearest TSS
ENST00000502646/Upstream/8577;
ENST00000507637/Downstream/4989;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/22524
,
chr5-CpG: 171/Downstream/35371
Upstream sequence
aatgGTATAAGCTGAGCTGCTAGCTGAGtgcattagtcatctattgctgcatgacagattgccacaaacttagtggcttagcacaatgcatgtttattac
Downstream sequence
ctcacagtttctttgggtgaggagtccagtcacatttagctgggtcctttgcaaggcgctgtaatcaaggtgttggttagggccaaggtcttatcagaag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Resting CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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