Basic Information
VIS ID
TVIS30013372
Fusion event
HIV-MAK integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
10804102/10803869 (Hg38)
End
10804102/10803869 (Hg38)
Orient
+
Location type
Exonic
Target gene
MAK
miRNAs that regulate target gene
hsa-mir-1273e ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6134 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-34b-3p ; hsa-mir-6771-5p ; hsa-mir-6746-5p ; hsa-mir-338-3p ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-634
Nearest miRNA
hsa-mir-3691/Upstream/364075; hsa-mir-10398/Downstream/5337687;
Nearest TSS
ENST00000381078/Upstream/33792; ENST00000436249/Downstream/27010;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/55984, chr6-CpG: 67/Downstream/33996
Upstream sequence
CACTTGTCCCTGGGAAAAGTGGCCTTAACATATAGAGTTCAGCCATGATACTTCCAACAGCCCACACATCAATGGGAGAACTATAAACTGAAGATCTCAG
Downstream sequence
TAAAACTTCAGGGGCACGATACCTATGAAAATAGAGAACAAAAGAGGTAATTTTGATTGCAATTTCAAAGGTGGATGGGCAGTAGCATTCTACGCTGTGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate