Basic Information
VIS ID
TVIS30013413
Fusion event
HIV-WDR46 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.32
Reference genome
GRCh37/hg19
Start
33250191/33282414 (Hg38)
End
33250191/33282414 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
WDR46
miRNAs that regulate target gene
hsa-mir-760 ; hsa-mir-345-5p ; hsa-mir-339-5p ; hsa-mir-324-3p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-1236/Upstream/74470; hsa-mir-10398/Downstream/4813;
Nearest TSS
ENST00000381078/Upstream/1503; ENST00000374610/Downstream/5015;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/4917, chr6-CpG: 32/Downstream/6348
Upstream sequence
AATCAGCGCCCTGACTTTACCAAAGAGAAAGGCCATCAGTGCAAACCAGGAATTACCGAGCGCTCGTGGAACACAGGGTCACATCCTTTGGTGAACTAAC
Downstream sequence
AACTCAAGGATGCATGCTGGCTCTTCTCCCCTCCACACACCCATCTATGGGACCCCTGGGTAAAGACCAGCCCAGTGCCAAATGGGAGTCTACTGTACTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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