Basic Information
VIS ID
TVIS30013442
Fusion event
HIV-POLH integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
43558637/43590900 (Hg38)
End
43558637/43590900 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
POLH
miRNAs that regulate target gene
hsa-mir-183-5p ; hsa-mir-135a-5p ; hsa-mir-135b-5p ; hsa-mir-2053 ; hsa-mir-3152-3p ; hsa-mir-3662 ; hsa-mir-383-3p ; hsa-mir-5197-5p ; hsa-mir-569 ; hsa-mir-8066
Nearest miRNA
hsa-mir-10398/Upstream/156280; hsa-mir-10524/Downstream/663306;
Nearest TSS
ENST00000381078/Upstream/14526; ENST00000508232/Downstream/462;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/14561, chr6-CpG: 68/Downstream/38153
Upstream sequence
taatcccagctacttgggaggctgagacaggagaatcacttgagtccaggaggcggagggtgcagtgagccgagattgcgccactgtactccagcctggg
Downstream sequence
tggcgacagagcaagactctgtctcaaaaaaaaaaaagaaaaaaaaaaaaaaGATGTAACATGTAAACTTTGCTTTTGCTGCTGAACAATTGCATAAAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate