Basic Information
VIS ID
TVIS30013489
Fusion event
HIV-SASH1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
148659708/148338572 (Hg38)
End
148659708/148338572 (Hg38)
Orient
+
Location type
Intronic
Target gene
SASH1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-93-5p ; hsa-mir-181a-5p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-3944-5p ; hsa-mir-548q ; hsa-mir-8083 ; hsa-mir-4700-3p ; hsa-mir-4744 ; hsa-mir-4773 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-7156-3p ; hsa-mir-1262 ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-4325 ; hsa-mir-4504 ; hsa-mir-4701-3p ; hsa-mir-508-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-10398/Upstream/7654689; hsa-mir-1202/Downstream/2764103;
Nearest TSS
ENST00000381078/Upstream/55164; ENST00000470750/Downstream/4021;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/829146, chr6-CpG: 79/Downstream/3717
Nearby gene
SASH1(No orient, 4021)
Nearest cancer related gene
SASH1(TSG, No orient, 0)
Upstream sequence
tgattctgccccatgtagctgtgttcacttggacttatcattcaagttctctggagcctacttcctcatctgtaaaatgaaggatttgacctagatcttt
Downstream sequence
ttcgaggcccttttcCATTTCCATGAGGTAGAATTCTAATATAAAACGTTCTTGGTAAATGATATCCTATATGACTCTGAAGTTGTGATGATGATGATGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate