Basic Information
VIS ID
TVIS30013509
Fusion event
HIV-MAD1L1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
2079826/2040191 (Hg38)
End
2079826/2040191 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7B
Target gene
MAD1L1
miRNAs that regulate target gene
hsa-mir-149-5p ; hsa-mir-20a-5p
Nearest miRNA
hsa-mir-339/Upstream/195938; hsa-mir-10399/Downstream/217324;
Nearest TSS
ENST00000635602/Upstream/59400; ENST00000454650/Downstream/39822;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/19695, chr7-CpG: 24/Downstream/9767
Nearest cancer related gene
MAD1L1(TSG, No orient, 0)
Upstream sequence
accttccagagataaaggctgtaaaggaatactacgaacagctgcatgccgaaaattaataacggaggtgaaatgaacaaactcctgaaaagacaaaagc
Downstream sequence
taccaaaactgactcaagagaaacacagacaacctgagtagacccacagaacagcaaagacactggattagtTTTGAAGACGCTGCCTGCTGCCTCTGCG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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