Basic Information
VIS ID
TVIS30013549
Fusion event
HIV-MAGI2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
77905406/78276089 (Hg38)
End
77905406/78276089 (Hg38)
Orient
-
Location type
Intronic
Target gene
MAGI2
miRNAs that regulate target gene
hsa-mir-655-3p ; hsa-mir-487b-3p ; hsa-mir-134-5p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-3944-5p ; hsa-mir-5690 ; hsa-mir-4660 ; hsa-mir-4704-5p ; hsa-mir-3912-5p ; hsa-mir-487a-3p
Nearest miRNA
hsa-mir-10525/Upstream/2360820; hsa-mir-10399/Downstream/13927926;
Nearest TSS
ENST00000635602/Upstream/78233; ENST00000428298/Downstream/9679;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/235349, chr7-CpG: 26/Downstream/1176160
Upstream sequence
CATGTGATTATTACCCTTTCCATTTTGAATTCTACTCAGGAAACTGACAGAGAAAGCATAAACTCATATTTCATCTCCCTAATTACTGGTCTAGGGAAGC
Downstream sequence
AAGAGATCTAAGGACTTAGTCAATGAATAATATAAAAATACAGTCAGCAGATCATAAATATTTATTGCTACATCAAAAGTCTGCTAGTCGATCTTTCAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate