Basic Information
VIS ID
TVIS30013566
Fusion event
HIV-KMT2E integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
104644567/105004120 (Hg38)
End
104644567/105004120 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
KMT2E
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1301-3p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-10525/Upstream/2532589; hsa-mir-10399/Downstream/9649225;
Nearest TSS
ENST00000635602/Upstream/62914; ENST00000480368/Downstream/8904;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/19719, chr7-CpG: 131/Downstream/8552
Nearby gene
KMT2E-AS1(No orient, 6422)
Upstream sequence
TAAAACCATGCTGACTGCAAATATGTTGTACTCTACTGCCCCACCCTTTCCCTAATGAAACCCAGAACTATCTGCCTCCTAATCCAAAAATTCTATTTCC
Downstream sequence
TCTGTGAAACACATTACCCCATGAACTGGGATATCTGGCTGAATGCTTACAGTACTTGGTTACTTACTGATGTGGCTTAATCCCAAACTAGATTATAAAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate