Basic Information
VIS ID
TVIS30013570
Fusion event
HIV-COG5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
107126017/107485572 (Hg38)
End
107126017/107485572 (Hg38)
Orient
-
Location type
Intronic
Target gene
COG5
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-320a ; hsa-mir-3978 ; hsa-mir-4261 ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-610 ; hsa-mir-181a-2-3p ; hsa-mir-497-3p
Nearest miRNA
hsa-mir-10525/Upstream/5014041; hsa-mir-10399/Downstream/7167773;
Nearest TSS
ENST00000635602/Upstream/4630; ENST00000467916/Downstream/62760;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/315688, chr7-CpG: 59/Downstream/78097
Upstream sequence
TTTATATTAACACATATGCTTACCAATTTTACAATGTAACTAGCTTCTCAAACTACATAAATGTTTCTAAAAACTTAGTGAATAACATGTCACAGAATCT
Downstream sequence
AGTGACACAAATACACCAGACTAAATTGTCTGACAACAGTAATCATAAATCCCAGTTACTATAGTATACAAGTCTTTTATCTTGTAAGCACTGAAAAAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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