Basic Information
VIS ID
TVIS30013574
Fusion event
HIV-MDFIC integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
114652932/115012878 (Hg38)
End
114652932/115012878 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7G
Target gene
MDFIC
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-132-3p ; hsa-mir-221-3p ; hsa-mir-376a-2-5p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-3668 ; hsa-mir-3935 ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-5002-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-659-3p ; hsa-mir-487b-5p ; hsa-mir-487a-5p ; hsa-mir-8054 ; hsa-mir-548l ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-497-3p
Nearest miRNA
hsa-mir-10525/Upstream/359423; hsa-mir-10399/Downstream/2007333;
Nearest TSS
ENST00000635602/Upstream/79009; ENST00000460471/Downstream/66080;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/90103, chr7-CpG: 71/Downstream/1197438
Upstream sequence
accagcttgtccaacaaggtaaaacctcatctctactaaaaatacaaaaaattaaccaggcatggtggccggcacctgtagtcccagctactggggaggc
Downstream sequence
tgaggcaggaaaatcgcttgaacccaggaggcggaggttgcaatgagccaagatcgcgccactgcactccagcctgggtgacagagtaagactctgtctc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate