Basic Information
VIS ID
TVIS30013589
Fusion event
HIV-DGKI integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q33
Reference genome
GRCh37/hg19
Start
137101439/137416693 (Hg38)
End
137101439/137416693 (Hg38)
Orient
+
Location type
Intronic
Target gene
DGKI
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-4786-3p ; hsa-mir-4635 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p
Nearest miRNA
hsa-mir-10525/Upstream/513399; hsa-mir-10399/Downstream/707065;
Nearest TSS
ENST00000635602/Upstream/20720; ENST00000418554/Downstream/36501;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/252094, chr7-CpG: 117/Downstream/429686
Upstream sequence
gaagctattgaagagctaaaagcaaaCCAGGAGAGCATATAAATGTCCTTAAGCATGTCAGTGTGAGTCTGCTTCCCCCCCTCTGGAAACAGTTAAGTTC
Downstream sequence
CTACTCTTCGCTCCTTTTCTCCCCATAGCCAACATTATAGCATCTTTCAGCTTGTACCCCATATCGCTCCCAAGCATTGTTATTTATGTTTGTTGGTTTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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