Basic Information
VIS ID
TVIS30013625
Fusion event
HIV-TUSC3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
GRCh37/hg19
Start
15501085/15643576 (Hg38)
End
15501085/15643576 (Hg38)
Orient
+
Location type
Intronic
Target gene
TUSC3
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-26b-5p ; hsa-mir-1229-3p ; hsa-mir-25-3p ; hsa-mir-181a-5p ; hsa-mir-30e-5p
Nearest miRNA
hsa-mir-124-1/Upstream/790066; hsa-mir-10400/Downstream/2038002;
Nearest TSS
ENST00000518652/Upstream/20496; ENST00000511342/Downstream/30187;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/102798, chr8-CpG: 46/Downstream/1357959
Upstream sequence
TTGTATACACTTCAACATATTTTATGTTCATATACAGTTTTGCTTTAAAATATGTATTTGGATCACATATGTTAGAATTGTTTTCCAAGGAAAGATCTAC
Downstream sequence
TTAGGTCTGATGAAGAAAATGGATGCACAGGGAACAGCTTTAAGAAACACAACCTCTTTATCTTACATCTAGTGAATTATTCAGTCAATTACAATATGGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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