Basic Information
VIS ID
TVIS30013703
Fusion event
HIV-MOB3B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
27384061/27384063 (Hg38)
End
27384061/27384063 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
MOB3B
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-122-5p ; hsa-mir-181a-5p ; hsa-mir-98-5p ; hsa-mir-4776-3p ; hsa-mir-192-3p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-2114-5p ; hsa-mir-4307 ; hsa-mir-33a-3p ; hsa-mir-409-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-1227-3p ; hsa-mir-455-5p ; hsa-mir-148a-5p
Nearest miRNA
hsa-mir-101-2/Upstream/5871878; hsa-let-7a-1/Downstream/1479563;
Nearest TSS
ENST00000422679/Upstream/86924; ENST00000448858/Downstream/7671;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/427291, chr9-CpG: 27/Downstream/144296
Upstream sequence
cccttccaggaaatttcctggtatagataagcattataaaggctctgagaaattctacagtaaagaaacctgcttattttcaatgtggtgtttcccaaac
Downstream sequence
ctacttagccacagaatccttttctATATAATAGAAACTTTGGGGAATATTGAAGTTACCCAACTAAACTTTGACAGCCCTGCAAGGGAGGAATTATTAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate