Basic Information
VIS ID
TVIS30013715
Fusion event
HIV-GNAQ integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
80360081/77745165 (Hg38)
End
80360081/77745165 (Hg38)
Orient
-
Location type
Intronic
Target gene
GNAQ
miRNAs that regulate target gene
hsa-mir-142-3p ; hsa-mir-128-3p ; hsa-mir-21-5p ; hsa-mir-5589-3p ; hsa-mir-653-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-5579-3p ; hsa-mir-3613-3p ; hsa-mir-501-5p ; hsa-mir-500a-5p ; hsa-mir-4668-3p ; hsa-mir-129-5p ; hsa-mir-6885-3p ; hsa-mir-767-5p ; hsa-mir-3130-3p ; hsa-mir-3653-3p ; hsa-mir-3658 ; hsa-mir-4511 ; hsa-mir-548b-3p ; hsa-mir-4775 ; hsa-mir-590-3p
Nearest miRNA
hsa-mir-101-2/Upstream/6935081; hsa-let-7a-1/Downstream/6224583;
Nearest TSS
ENST00000422679/Upstream/96858; ENST00000536374/Downstream/285439;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/96380, chr9-CpG: 181/Downstream/285765
Nearest cancer related gene
GNAQ(OG, No orient, 0)
Upstream sequence
GGCTCTGGAAACATTCAAGTGATAATGTTTACTAACACAGAGGAGTGGAGGACTGAACTGGTTCAGTTCTGCGAGAGGCAGGGAAAAGTCGAGTAGGCAC
Downstream sequence
CTAGTTCTGTAACTGGGCTGAACAAGAGGCAGGACAGATGGGAGAAACAGCTGGGTTCTGCCATCTTTACACTCTCCAACACCCAGACTCCTAACCCAGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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