Basic Information
VIS ID
TVIS30013788
Fusion event
HIV-WDR5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.2
Reference genome
GRCh37/hg19
Start
137016571/134151449 (Hg38)
End
137016571/134151449 (Hg38)
Orient
-
Location type
Intronic
Target gene
WDR5
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-30c-5p ; hsa-mir-3189-5p ; hsa-mir-5699-5p ; hsa-mir-4758-3p ; hsa-mir-6865-3p
Nearest miRNA
hsa-let-7a-1/Upstream/1099390; hsa-mir-126/Downstream/227962;
Nearest TSS
ENST00000422679/Upstream/15361; ENST00000608264/Downstream/17320;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/14573, chr9-CpG: 23/Downstream/2024
Upstream sequence
TCTCGTGCTTGGGGAATGATTTGTCCACGTGTGACCCGAGCCTGTTCCCCGCTGCTGGCATCTGTGCAGTAGAATTGTGGGTGCTAACACAGTGGGCTCT
Downstream sequence
GCTTCCAGAATGCGTCTGTATTGGCAGAAATCACAGAAACCCTGAAATTGGAACAATGTAAATGCCTGGCTTGTACCTTCTGGGAATAGTCCAGAAGACT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate