Basic Information
VIS ID
TVIS30013828
Fusion event
HIV-ATP7A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
77231213/77975717 (Hg38)
End
77231213/77975717 (Hg38)
Orient
+
Location type
Intronic
Target gene
ATP7A
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-9-5p ; hsa-mir-122-5p ; hsa-mir-320a ; hsa-mir-495-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-4517 ; hsa-mir-3529-3p ; hsa-mir-5688 ; hsa-mir-1277-5p ; hsa-mir-297 ; hsa-mir-493-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-1257 ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-4501 ; hsa-mir-5579-5p ; hsa-mir-5011-5p ; hsa-mir-5580-3p ; hsa-mir-5583-3p ; hsa-mir-3065-5p ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p
Nearest miRNA
hsa-let-7f-2/Upstream/970216; hsa-mir-105-1/Downstream/925477;
Nearest TSS
ENST00000429181/Upstream/6079; ENST00000477335/Downstream/89471;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/64919, chrX-CpG: 76/Downstream/128089
Upstream sequence
tagctgggactacaggtgcacgtcaccattcctgggtaattttttgtacttttagtagaaacggggtttcaccatgttggccaggctggcctggaactcc
Downstream sequence
tgacctcaggtgatccgcccgcctcggcctcccacagtattgggattacaggcatgagccaccacgcccagccTGAATTGCTTACCCTTAAACATGTTTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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