Basic Information
VIS ID
TVIS30013864
Fusion event
HIV-TKTL1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
GRCh37/hg19
Start
153541255/154312904 (Hg38)
End
153541255/154312904 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRAXE ; FRAXF
Target gene
TKTL1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-let-7f-2/Upstream/292915; hsa-mir-1184-1/Downstream/137416;
Nearest TSS
ENST00000429181/Upstream/7847; ENST00000465168/Downstream/7400;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/17082, chrX-CpG: 27/Downstream/19781
Nearest cancer related gene
TKTL1(OG, No orient, 0)
Upstream sequence
AGATACGTCAACTGCTTTGTTCTCTAATGTTGTTCGTATGTACACAGGATTCTTCATTTATTCTGGTCTCCATGGACGAACCAATTACTAGAGTGACATG
Downstream sequence
TAACTAACAGTTCGTAGGCAATAAAGAGAGGTTTGCCATTTTTAAAAAatacatttaggggtccaaagtgcagctgtgtcacgtggatagatactgtgta
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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