Basic Information
VIS ID
TVIS30013874
Fusion event
HIV-PLCG1-AS1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Nontumor
Disease
AIDS dementia (AD)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q12
Reference genome
GRCh37/hg19
Start
39737739/41109099 (Hg38)
End
39737739/41109099 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
PLCG1-AS1
Nearest miRNA
hsa-mir-103a-2/Upstream/2592467; hsa-mir-1-1/Downstream/59924;
Nearest TSS
ENST00000382410/Upstream/80281; ENST00000490253/Downstream/27861;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/79327, chr20-CpG: 175/Downstream/27490
Upstream sequence
CAAACTTTAGGATCAATGTTGACATCGTATTGCGTTTAGTCCTGTTAAAATACTCTCAGTGCCAAATACACACTTCTGCCTTTTTTCTCTTTAGAGTCTA
Downstream sequence
GAATTCTGTGGGGTTCCAAAAATGTATGTGCTTACAACCTTTTATATGTAACCACCTAGGGATTAAAGGGCTAAATGTGAAGGAAAGTATCTTTACAATA
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
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