Basic Information
VIS ID
TVIS30013881
Fusion event
HIV-TBC1D15 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Nontumor
Disease
AIDS dementia (AD)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
72291023/71897243 (Hg38)
End
72291023/71897243 (Hg38)
Orient
-
Location type
Intronic
Target gene
TBC1D15
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-484 ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-369-3p ; hsa-mir-140-3p ; hsa-mir-3120-3p ; hsa-mir-338-5p ; hsa-mir-7703 ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-196a-3p ; hsa-mir-661 ; hsa-mir-4696 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-130b-5p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-451b ; hsa-mir-508-5p ; hsa-mir-4432 ; hsa-mir-6501-3p ; hsa-mir-548s ; hsa-mir-4684-5p ; hsa-mir-3926 ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4698 ; hsa-mir-888-5p ; hsa-mir-6771-3p ; hsa-mir-1273e ; hsa-mir-1295b-5p ; hsa-mir-1912 ; hsa-mir-25-5p ; hsa-mir-423-3p ; hsa-mir-4329 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4768-3p ; hsa-mir-658 ; hsa-mir-6746-5p ; hsa-mir-6771-5p
Nearest miRNA
hsa-let-7i/Upstream/2312420; hsa-mir-1178/Downstream/7522014;
Nearest TSS
ENST00000382841/Upstream/26; ENST00000479971/Downstream/604;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/57388, chr12-CpG: 160/Downstream/374660
Nearest cancer related gene
TBC1D15(OG, No orient, 0)
Upstream sequence
AGAAATATATTTGCTATTTAGATTAATTACCTTTAAGTTACTTTTCTGATACTCTTATAATGGATCCTTCATTCTTTTTGGAAGAGTATTTCTATTTTAA
Downstream sequence
GTTATTCCTCAGACTTGAAAGGAAACACAGACCAACTTTCCAGGTACAACTTCTTGTTCTCAGTTGTCAGTCTAGCCTTTGATTTAAAGCTATTTTCAGT
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
Curate