Basic Information
VIS ID
TVIS30013883
Fusion event
HIV-chr2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Nontumor
Disease
AIDS dementia (AD)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
38996372/38769230 (Hg38)
End
38996372/38769230 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1301/Upstream/3297744; hsa-mir-10b/Downstream/8608445;
Nearest TSS
ENST00000437798/Upstream/17696; ENST00000409566/Downstream/8955;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/17688, chr2-CpG: 42/Downstream/106290
Nearby gene
GEMIN6(No orient, 8955)
Upstream sequence
tgacctcaggtgatccacccaccttggcctcccaaattgctgggattacaggtgtcagccactgggcctggccccccatatacatttcttcatatgtatc
Downstream sequence
ctttataatattgtttataataaactggtaaatgtTGGATCAGGTAGTGATTCATATAGGAGTACTGAGCTTGAAAGAATCATGAGAACTGGCCCAACAT
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
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