Basic Information
VIS ID
TVIS30013888
Fusion event
HIV-chr1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
AIDS-associated lymphoma (AAL)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
GRCh37/hg19
Start
27972042/27645531 (Hg38)
End
27972042/27645531 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/1090938; hsa-mir-101-1/Downstream/3093625;
Nearest TSS
ENST00000473358/Upstream/10254; ENST00000430683/Downstream/17191;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/10232, chr1-CpG: 62/Downstream/14263
Nearby gene
FGR(No orient, 10315)
Nearest cancer related gene
FGR(OG, No orient, 10315)
Upstream sequence
GGAGGAGGGTTTCTAGAGTGGGTGGACTCTACCTGCCTGGAGTGCAGTGAGGAAGCCAGTGGGGTCATCACACAGCCCCCTCCCACCAGGAGTGCTGACG
Downstream sequence
CATCCCTACACTGACGTCCAGGAGCCATCTGAGGCCTACGAGGACATGAGAACAAGCAGGGACCAGAGTGAGGACCACCGTAGTGCACTCTGGGGAGGCC
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
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