Basic Information
VIS ID
TVIS30013892
Fusion event
HIV-ANKRD17 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
AIDS-associated lymphoma (AAL)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
74043424/73177707 (Hg38)
End
74043424/73177707 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANKRD17
miRNAs that regulate target gene
hsa-mir-23b-3p ; hsa-mir-1-3p ; hsa-mir-16-5p ; hsa-mir-424-5p ; hsa-mir-186-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-549a ; hsa-mir-4699-3p ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-885-5p ; hsa-mir-6504-3p
Nearest miRNA
hsa-mir-12113/Upstream/6900779; hsa-mir-1243/Downstream/3395861;
Nearest TSS
ENST00000502981/Upstream/23772; ENST00000502790/Downstream/45332;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/107774, chr4-CpG: 62/Downstream/80981
Upstream sequence
agaaagcaggggagggaaaaaATATGTTAACATAATTAACAATGGTAAACACAGTGCAACCCTAAAAAGTTCAACATGACATCTAAGCCTGTTGATTAAC
Downstream sequence
AAAAGAAGAAATTTTTTTGTGGAAGAATTCAAAACTTTATTTCTCATATGCAGCCTAATTTTCTTTACTAATATTCTTTTCTACTTTAATTTGGTTATTA
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
Curate