Basic Information
VIS ID
TVIS30013894
Fusion event
HIV-FLT3LG integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
AIDS-associated lymphoma (AAL)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
49984278/49481021 (Hg38)
End
49984278/49481021 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
FLT3LG
Nearest miRNA
hsa-mir-10395/Upstream/172153; hsa-let-7e/Downstream/19764;
Nearest TSS
ENST00000633603/Upstream/2104; ENST00000486930/Downstream/6533;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/16427, chr19-CpG: 51/Downstream/6157
Upstream sequence
ctcaggaggctgaggaaggagaattgcttgaacccaggaggcggaggttgcagtgagccgagattgcgccactggactccagcctgagtgacagagctag
Downstream sequence
actccgtctcaaaaaaaaaaaaaaaaaagaaaaggaaagaCCCCTCTGGGGCCACGGAGACAGACTGGAGACCAAGCCGGAGGCTGTGGGAAGGCCCAGG
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
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