Basic Information
VIS ID
TVIS30013895
Fusion event
HIV-ZNF331 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
AIDS-associated lymphoma (AAL)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
54039861/53536607 (Hg38)
End
54039861/53536607 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZNF331
miRNAs that regulate target gene
hsa-mir-20a-5p ; hsa-mir-4474-3p ; hsa-mir-7108-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-6815-3p ; hsa-mir-5696 ; hsa-mir-6828-5p ; hsa-mir-4729 ; hsa-mir-6510-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-31-5p ; hsa-mir-661 ; hsa-mir-873-3p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-5586-3p ; hsa-mir-508-5p
Nearest miRNA
hsa-let-7e/Upstream/1254714; hsa-mir-10394/Downstream/130072;
Nearest TSS
ENST00000633603/Upstream/284; ENST00000504940/Downstream/646;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/14938, chr19-CpG: 100/Downstream/951
Upstream sequence
AGTCAGTATTATTAGGAAATGTACTCTATGTCATTGTATAACAGACCATGGTTTAATCTGATTTTCCTTTATCCTCCACTGCAAGATTTTCATTTTTAAA
Downstream sequence
AATTATTCTCgactgggtgtggtggctcacgcctgtaattcctgcactttgtgaggccgaggcaggcggatcacctgaggtcgggagttcgagtccagcc
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
Curate