Basic Information
VIS ID
TVIS30013896
Fusion event
HIV-KIAA0319L integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
AIDS-associated lymphoma (AAL)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
35986802/35521201 (Hg38)
End
35986802/35521201 (Hg38)
Orient
-
Location type
Intronic
Target gene
KIAA0319L
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-128-3p ; hsa-mir-423-3p ; hsa-mir-432-5p ; hsa-mir-218-5p ; hsa-mir-5689 ; hsa-mir-571 ; hsa-mir-219a-1-3p ; hsa-mir-129-5p ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-431-5p ; hsa-mir-4294 ; hsa-mir-3194-3p ; hsa-mir-924
Nearest miRNA
hsa-mir-12136/Upstream/851507; hsa-mir-101-1/Downstream/1640362;
Nearest TSS
ENST00000473358/Upstream/14334; ENST00000459931/Downstream/33786;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/251947, chr1-CpG: 95/Downstream/35878
Upstream sequence
aggctgaggcgggtggatcatttgaggtcaggagttcgagaccagcttggccaacacagtgaaaccccgtctctaccaaaaatacaaaaagttagctggg
Downstream sequence
caggtgcacacctgtaatcccagcaactgggggaggttgaggcaagagaatcacttgaacccagaagacggaggttgcagtgagccgagattgcaccact
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
Curate