Basic Information
VIS ID
TVIS30013897
Fusion event
HIV-AEBP2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
AIDS-associated lymphoma (AAL)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
19645761/19492827 (Hg38)
End
19645761/19492827 (Hg38)
Orient
-
Location type
Intronic
Target gene
AEBP2
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-103a-3p ; hsa-mir-101-3p ; hsa-mir-484 ; hsa-mir-328-3p ; hsa-let-7e-5p ; hsa-mir-3686 ; hsa-mir-4775 ; hsa-mir-3607-3p ; hsa-mir-4778-5p ; hsa-mir-5580-3p ; hsa-mir-590-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/1819433; hsa-let-7i/Downstream/4719594;
Nearest TSS
ENST00000382841/Upstream/52246; ENST00000398731/Downstream/7266;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/52076, chr12-CpG: 24/Downstream/448376
Upstream sequence
gggcctaggcaaatggatggtttgagcccaggagttcaggaccagcttacccaacatggtgaaacccccttttgacaaaaaatgcaacaacaacaaaata
Downstream sequence
ttagtagagtgtggtggcgtgtgcctatagtaccaccacctgggaggctgaggtgggaggatcacttgagcctgggaggttgaggctgcagtgagccgag
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
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