Basic Information
VIS ID
TVIS30013901
Fusion event
HIV-CYP19A1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
AIDS-associated lymphoma (AAL)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
51508682/51216485 (Hg38)
End
51508682/51216485 (Hg38)
Orient
+
Location type
Intronic
Target gene
CYP19A1
miRNAs that regulate target gene
hsa-mir-378a-3p ; hsa-let-7f-5p ; hsa-mir-106a-5p ; hsa-mir-19b-3p ; hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-515-5p
Nearest miRNA
hsa-mir-10393/Upstream/856075; hsa-mir-11181/Downstream/25705;
Nearest TSS
ENST00000557528/Upstream/498; ENST00000559672/Downstream/2063;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/120927, chr15-CpG: 69/Downstream/125042
Upstream sequence
ggattacaggcacctgccaccacgcccagctaattttttgtatttttagtaaagacagagtttcaccatgttggtcaggttggtctcaaactcctgacct
Downstream sequence
caggtgatccacccacctcggcctcccaaagtgctgggattgcaggcatgagccattgcacctggcccccatagtctgcttttatttgcctagtcctgaa
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
Curate