Basic Information
VIS ID
TVIS30013902
Fusion event
HIV-INPP5B integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
AIDS-associated lymphoma (AAL)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
38381833/37916161 (Hg38)
End
38381833/37916161 (Hg38)
Orient
-
Location type
Intronic
Target gene
INPP5B
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-6807-5p ; hsa-mir-521 ; hsa-mir-4796-5p ; hsa-mir-1284 ; hsa-mir-187-3p ; hsa-mir-1537-3p
Nearest miRNA
hsa-mir-12136/Upstream/415167; hsa-mir-101-1/Downstream/173070;
Nearest TSS
ENST00000473358/Upstream/27817; ENST00000486563/Downstream/15588;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/55834, chr1-CpG: 53/Downstream/15403
Upstream sequence
GGCCTACCACTGAATTGGTGTCTGGGtttttctttttcctttttttttttgagatggagtctcgctctgtcacccaggctggagttcagtggtgcaatct
Downstream sequence
tggctcactacaatctctgcctcccaggttcaagcgattcttgtgccttagcctcccaagtagctaggattacaggcacccaccactacacccagcttat
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
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