Basic Information
VIS ID
TVIS30013903
Fusion event
HIV-SAE1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
AIDS-associated lymphoma (AAL)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47659738/47156481 (Hg38)
End
47659738/47156481 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
SAE1
miRNAs that regulate target gene
hsa-mir-1229-3p ; hsa-mir-615-3p ; hsa-mir-324-3p ; hsa-mir-151a-3p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-203a-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-4266 ; hsa-mir-4695-5p ; hsa-mir-4779 ; hsa-mir-1273g-5p ; hsa-mir-6816-3p ; hsa-mir-3651 ; hsa-mir-6779-3p ; hsa-mir-7976 ; hsa-mir-651-5p ; hsa-mir-299-5p ; hsa-mir-103b ; hsa-mir-129-2-3p ; hsa-mir-129-1-3p ; hsa-mir-4687-5p
Nearest miRNA
hsa-mir-10395/Upstream/447127; hsa-let-7e/Downstream/70461;
Nearest TSS
ENST00000633603/Upstream/25586; ENST00000601154/Downstream/66087;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/25374, chr19-CpG: 88/Downstream/69579
Upstream sequence
ggcaggagaatagcttgaactggggaggcggatgttgcagtgagccgagacggcaacactgcactccagcctggcgacagaacgagactctgtctccaaa
Downstream sequence
aaaaaaaGTTTTCTTTGCCTGTTTTTTTCCTTTTGCCAAATAACCTTTAATAAGAAAAATCCTTCAATGTTgtcttgctgtgtccaggctggagtggcac
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
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