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TVIS30013904
Basic Information
VIS ID
TVIS30013904
Fusion event
HIV-TBC1D5 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Tumor
Disease
Angioimmunoblastic lymphadenopathy (AILD)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
17443685/17402193 (Hg38)
End
17443685/17402193 (Hg38)
Orient
+
Location type
Intronic
Target gene
TBC1D5
miRNAs that regulate target gene
hsa-mir-375
;
hsa-mir-493-5p
;
hsa-mir-4446-5p
;
hsa-mir-3679-3p
;
hsa-mir-6086
;
hsa-mir-377-5p
;
hsa-mir-655-5p
;
hsa-mir-361-3p
;
hsa-mir-329-5p
;
hsa-mir-6779-3p
Nearest miRNA
hsa-mir-12127/Upstream/468933; hsa-let-7g/Downstream/1912655;
Nearest TSS
ENST00000440867/Upstream/30059;
ENST00000449613/Downstream/4527;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/516843
,
chr3-CpG: 58/Downstream/340377
Upstream sequence
ATTACCTGTGGTTTCATTTACTCTAAACCTGTGATTCCTCTGAATTATTTTCATTTTAAAGAAATTGTATTTGTTAAATATGTACTACAAACTTAGTAGT
Downstream sequence
AGTTCATGTCATCTTATTATTCAGTATTTATAACTTGCAAAGAAATGAATATCAGAGAGCGAGAGGCCTTGACATTATAATAGATTTAGCAGGAATTGAA
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
Sample Information
×
Sample name
case #3
Sample type
Tumor
Gender
Female
CpG Island Information
×
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