Basic Information
VIS ID
TVIS30013908
Fusion event
HIV-ATF7 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2003
PubMed ID
12843741
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
54006736/53612952 (Hg38)
End
54006736/53612952 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12A
Target gene
ATF7
miRNAs that regulate target gene
hsa-mir-769-5p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/555940; hsa-let-7i/Downstream/378786;
Nearest TSS
ENST00000382841/Upstream/69001; ENST00000566418/Downstream/13019;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/111423, chr12-CpG: 39/Downstream/13076
Upstream sequence
aattagttgggcatggtagcgcgcacctgtagtccctgctactcgggaggctgaggcacaaaaatcgcttgaacctgggaggcagaggttgcagtgagcc
Downstream sequence
aacctcacagcactgcactccagcctggacgacagagcgagactctgtctcaagaaaaaaaaaaGGCAAGTGAGGCCAATGCATTTTTAAAAAATTTCCC
Reference
Mack, K. D., et al. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J Acquir Immune Defic Syndr ,2003,33(3): 308-320.
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