Basic Information
VIS ID
TVIS30013927
Fusion event
HIV-ADD3 integration
Validated
Yes
Detection method
invPCR+RT-PCR
Data source
download(RID)
Sample type
T cell
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2004
PubMed ID
15163705
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
111811163/110051405 (Hg38)
End
111811163/110051405 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
ADD3
miRNAs that regulate target gene
hsa-mir-374b-5p ; hsa-mir-124-3p ; hsa-mir-24-3p ; hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-130a-5p ; hsa-mir-374a-5p ; hsa-mir-23c ; hsa-mir-155-5p ; hsa-mir-1202 ; hsa-mir-3972 ; hsa-mir-5006-5p ; hsa-mir-145-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-129-5p ; hsa-mir-4776-3p
Nearest miRNA
hsa-mir-107/Upstream/5783000; hsa-mir-202/Downstream/846685;
Nearest TSS
ENST00000439456/Upstream/34970; ENST00000473669/Downstream/25600;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/42808, chr10-CpG: 235/Downstream/156265
Junction sequence
AAGGTAAGGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Han, Y., et al. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J Virol ,2004,78(12): 6122-6133.
Curate