Basic Information
VIS ID
TVIS30013931
Fusion event
HIV-PIAS1 integration
Validated
Yes
Detection method
invPCR+RT-PCR
Data source
download(RID)
Sample type
T cell
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2004
PubMed ID
15163705
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
GRCh37/hg19
Start
68420045/68127707 (Hg38)
End
68420045/68127707 (Hg38)
Orient
+
Location type
Intronic
Target gene
PIAS1
miRNAs that regulate target gene
hsa-mir-424-5p ; hsa-mir-124-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-3171 ; hsa-mir-5683 ; hsa-mir-101-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5580-3p ; hsa-mir-4789-3p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-mir-1278 ; hsa-mir-1183 ; hsa-mir-340-5p
Nearest miRNA
hsa-mir-10393/Upstream/1630673; hsa-mir-11181/Downstream/674143;
Nearest TSS
ENST00000557528/Upstream/73131; ENST00000564009/Downstream/18955;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/72637, chr15-CpG: 64/Downstream/101373
Nearby gene
TLE3(No orient, 242735)
Nearest cancer related gene
PIAS1(TSG, No orient, 0)
Junction sequence
AAGGTGAATC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Han, Y., et al. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J Virol ,2004,78(12): 6122-6133.
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