Basic Information
VIS ID
TVIS30013942
Fusion event
HIV-KCNN1 integration
Validated
Yes
Detection method
invPCR+RT-PCR
Data source
download(RID)
Sample type
T cell
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2004
PubMed ID
15163705
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
17939839/17829030 (Hg38)
End
17939839/17829030 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
KCNN1
miRNAs that regulate target gene
hsa-mir-4796-3p ; hsa-mir-4256 ; hsa-mir-5702 ; hsa-mir-4750-3p ; hsa-mir-5193 ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-3065-3p ; hsa-mir-1306-5p ; hsa-mir-634 ; hsa-mir-378a-5p ; hsa-mir-7848-3p ; hsa-mir-4454 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-3621 ; hsa-mir-506-5p ; hsa-mir-892c-5p ; hsa-mir-6893-3p ; hsa-mir-370-3p
Nearest miRNA
hsa-mir-10395/Upstream/2379422; hsa-let-7e/Downstream/453047;
Nearest TSS
ENST00000633603/Upstream/7456; ENST00000602216/Downstream/13495;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/7469, chr19-CpG: 48/Downstream/2117
Junction sequence
AAGGTTATTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Han, Y., et al. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J Virol ,2004,78(12): 6122-6133.
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