Basic Information
VIS ID
TVIS30013955
Fusion event
HIV-FKBP5 integration
Validated
Yes
Detection method
invPCR+RT-PCR
Data source
download(RID)
Sample type
T cell
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2004
PubMed ID
15163705
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
35646989/35679212 (Hg38)
End
35646989/35679212 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
FKBP5
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-93-3p ; hsa-mir-328-3p ; hsa-mir-22-3p ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-6516-5p ; hsa-mir-550b-2-5p ; hsa-mir-4443 ; hsa-mir-455-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-4537 ; hsa-mir-5186 ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-1243 ; hsa-mir-3654 ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-302c-5p ; hsa-mir-7106-5p ; hsa-mir-6878-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-6133 ; hsa-mir-765 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-539-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4779 ; hsa-mir-6760-5p ; hsa-mir-7977 ; hsa-mir-3166 ; hsa-mir-3664-3p ; hsa-mir-5690 ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-4666a-5p ; hsa-mir-4740-5p ; hsa-mir-4272 ; hsa-mir-6816-3p ; hsa-mir-3169 ; hsa-mir-8080 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-4485-5p ; hsa-mir-511-5p ; hsa-mir-28-5p ; hsa-mir-3139 ; hsa-mir-3190-5p ; hsa-mir-3613-3p ; hsa-mir-3675-3p ; hsa-mir-3926 ; hsa-mir-4684-5p ; hsa-mir-4786-5p ; hsa-mir-548c-3p ; hsa-mir-548s ; hsa-mir-5589-5p ; hsa-mir-6771-3p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-708-5p
Nearest miRNA
hsa-mir-1236/Upstream/14423; hsa-mir-10398/Downstream/943224;
Nearest TSS
ENST00000381078/Upstream/134580; ENST00000471400/Downstream/9703;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/166835, chr6-CpG: 165/Downstream/8618
Nearby gene
FKBP5(No orient, 2351)
Junction sequence
AAGGTGACAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Han, Y., et al. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J Virol ,2004,78(12): 6122-6133.
Curate