Basic Information
VIS ID
TVIS30013974
Fusion event
HIV-MARK4 integration
Validated
Yes
Detection method
invPCR+RT-PCR
Data source
download(RID)
Sample type
T cell
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2004
PubMed ID
15163705
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50500224/49996967 (Hg38)
End
50500224/49996967 (Hg38)
Orient
+
Location type
UTR3
Fragile sites / regions
FRA19A
Target gene
MARK4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-30c-5p ; hsa-mir-3685 ; hsa-mir-4684-5p ; hsa-mir-3162-3p ; hsa-mir-7108-3p ; hsa-mir-3675-3p
Nearest miRNA
hsa-mir-10395/Upstream/63830; hsa-let-7e/Downstream/1209962;
Nearest TSS
ENST00000633603/Upstream/4057; ENST00000598809/Downstream/574;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/67086, chr19-CpG: 100/Downstream/27952
Junction sequence
AAGGTCTACC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Han, Y., et al. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J Virol ,2004,78(12): 6122-6133.
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