Basic Information
VIS ID
TVIS30013981
Fusion event
HIV-RNF213 integration
Validated
Yes
Detection method
invPCR+RT-PCR
Data source
download(RID)
Sample type
T cell
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2004
PubMed ID
15163705
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
75918743/77922661 (Hg38)
End
75918743/77922661 (Hg38)
Location type
Intronic
Target gene
RNF213
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-335-5p ; hsa-mir-423-3p ; hsa-mir-99b-5p ; hsa-mir-10a-5p ; hsa-mir-101-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-4635 ; hsa-mir-1303 ; hsa-mir-127-5p ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-4738-3p ; hsa-mir-4496 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-582-5p ; hsa-mir-216b-3p ; hsa-mir-603 ; hsa-mir-8485
Nearest miRNA
hsa-mir-10226/Upstream/525607; hsa-mir-1250/Downstream/1784515;
Nearest TSS
ENST00000595228/Upstream/38574; ENST00000588549/Downstream/36579;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/34415, chr17-CpG: 276/Downstream/35147
Junction sequence
AAGGTGACTG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Han, Y., et al. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J Virol ,2004,78(12): 6122-6133.
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