Basic Information
VIS ID
TVIS30013982
Fusion event
HIV-NFATC2 integration
Validated
Yes
Detection method
invPCR+RT-PCR
Data source
download(RID)
Sample type
T cell
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2004
PubMed ID
15163705
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
49538444/50921907 (Hg38)
End
49538444/50921907 (Hg38)
Orient
+
Location type
Intronic
Target gene
NFATC2
miRNAs that regulate target gene
hsa-mir-184 ; hsa-mir-526b-5p ; hsa-mir-7157-5p ; hsa-mir-4310 ; hsa-mir-451b ; hsa-mir-5571-5p ; hsa-mir-4512 ; hsa-mir-3157-5p ; hsa-mir-20b-3p ; hsa-mir-1304-3p ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-1183 ; hsa-mir-10a-3p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-3941 ; hsa-mir-496 ; hsa-mir-6504-3p ; hsa-mir-4700-3p ; hsa-mir-8485 ; hsa-mir-4459 ; hsa-mir-603 ; hsa-mir-129-5p ; hsa-mir-489-3p ; hsa-mir-514a-3p ; hsa-mir-514b-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/307122; hsa-mir-1-1/Downstream/530998;
Nearest TSS
ENST00000382410/Upstream/12116; ENST00000614698/Downstream/6825;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/81102, chr20-CpG: 143/Downstream/8624
Nearest cancer related gene
NFATC2(TSG, No orient, 0)
Junction sequence
AAGGTGAGGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Han, Y., et al. Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J Virol ,2004,78(12): 6122-6133.
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