Basic Information
VIS ID
TVIS30013989
Fusion event
HIV-STX17 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
102689318/99927036 (Hg38)
End
102689318/99927036 (Hg38)
Orient
-
Location type
Intronic
Target gene
STX17
miRNAs that regulate target gene
hsa-mir-30b-5p ; hsa-mir-5089-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-210-5p ; hsa-mir-4313 ; hsa-mir-1233-3p ; hsa-mir-6506-5p ; hsa-mir-1225-3p ; hsa-mir-619-5p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-6752-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-512-3p ; hsa-mir-6769a-3p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-let-7a-1/Upstream/1697819; hsa-mir-12126/Downstream/6673892;
Nearest TSS
ENST00000422679/Upstream/20294; ENST00000525579/Downstream/1742;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/19845, chr9-CpG: 69/Downstream/171457
Upstream sequence
tggtcacatgtaccatttctagccttgggtgatcttcaggaattattctacctgttctttttctgaccacgggttgttccctcacatgcatgtgtggagg
Downstream sequence
agtcctttgttgaagactcaaaaggaaaaccctgcagatctctggagttctctctcagtgtattcctctcctctcagtgcaactagcccttcaccatgca
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate